Saturday, August 1, 2020

Breakthrough (Part 6): CBInsights

"The goal is to turn data into information, and information into insight." -- Carly Fiorina

CB Insights (www.cbinsights.com) offers services specifically designed to use unstructured big data to help identify technology startups with significant potential.

A subscription to CB Insights services includes access to databases the company has created to identify these startups.

Whether you are interested in investing in or employing emerging technologies, it is worth your time to explore the services and databases offered by CB Insights.

Here is some background on the company. Some of it is from the CB Insights Web site. Some of it is from third party sources.

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The CB Insights tech market intelligence platform analyzes millions of data points on venture capital, startups, patents, partnerships and news mentions to help you see tomorrow's opportunities, today.
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Automate news tracking and funding alerts on companies and industries you care about. Using CB Insights you can streamline your due diligence on potential targets by analyzing their health and potential all in one place.
source: www.cbinsights.com
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How Saudi Arabia Is Hedging Against An Oil-Less Future
October 2, 2018
Despite ranking first in global oil exports, Saudi Arabia is investing in electric vehicles and renewable energy, in addition to other tech startups. We dive into where Saudi investors have been most focused in the renewables and energy space.
Saudi Arabia — the largest exporter of oil in the world — is investing in electric vehicles.
The country’s sovereign wealth fund, the Public Investment Fund of Saudi Arabia (PIF), was the first Saudi-based investor to enter the EV space.
In recent months, the fund has commanded the attention of the press, largely driven by its investments in Lucid Motors and in Tesla — as well as its rumored buyout of Tesla that ultimately fell through.

Investing in EV companies, in addition to companies pioneering technology in alternative energy, helps the country hedge against its oil export business.
In addition, Saudi Arabia was hit hard by the collapse of crude oil prices in 2014, which weighed heavily on the profitability of its oil business.
These recent investments in EVs and renewables are part of a broader economic diversification strategy called Saudi Vision 2030, pioneered by Crown Prince Mohammed bin Salman, in an attempt to lessen the kingdom’s dependence on oil.
As part of the plan, PIF is planning to reach $2T in assets under management by 2030, up from an estimated $250B currently. To finance these investments, Prince bin Salman has been redirecting the country’s oil revenues to the fund, and recently, PIF announced it had raised an $11B bank loan.
While PIF has driven the majority of funding in recent months, a number of venture capital firms and corporates in the kingdom are also funneling capital into tech firms, which could help diversify the economy and bring new jobs into the region.
To understand where Saudi investors are most focused in the alternative energy space, we used our Business Social Graph tool to map out their investments in electric vehicles and renewable energy since the launch of Saudi Vision 2030 in April 2016.

Breaking into electric vehicles
In September, PIF poured $1B into Lucid Motors, an EV manufacturer that had recently been struggling to raise enough capital to launch production for its first luxury EV, the Lucid Air. Lucid plans to use the funding for engineering development and testing of the Air, which is due in 2020. The company also plans to build its first factory in Casa Grande, Arizona.
The investment in Lucid came just six weeks after Elon Musk tweeted that he would take Tesla private at $420 a share, suggesting that PIF would back the company’s move.
While many view the Lucid investment as PIF passing over Tesla, it’s important to note that in August, PIF had purchased a roughly 5% stake in Tesla, which would equate to an investment of almost $2B.
Both of these investments highlight the fund’s attempt to hedge its bets on oil, in addition to taking advantage of the long-term opportunity in EVs.
Renewable ENergy also a focus among saudi investors
PIF, as well as a number of other Saudi VC funds and corporations, are also investing in clean energy.
The fund announced an investment in Saudi power company ACWA Power in July, taking a 15.2% direct stake in the company. ACWA is currently building out its renewable energy capabilities.
In February, ACWA won a contract to develop a 300 megawatt solar plant in Saudi Arabia worth $300M.
PIF has also expressed interest in investing in its own solar project, announcing in May that it was in talks with banks to fund a solar farm in partnership with SoftBank that would have a capacity of 200 gigawatts — 100 times larger than the largest solar farm ever proposed — and would cost $200B to build.
In October, the fund announced that the project had been shelved for a broader, more practical strategy to support renewable energy. It’s worth noting that government-driven solar projects have been cancelled in the past.
The country is also planning to invest $7B in renewable energy in 2018, mainly to create seven new solar plants and a wind farm. These investments are intended to help the country reach its goal for 2023 to have renewables driving at least 10% of its power generation.
Outside of PIF, a number of VCs and Saudi holding companies have also invested in renewable energy.
In December 2017, Saudi Aramco’s venture arm led a $9.4M Series B investment in NexWafe, a spin-off of solar energy research firm Fraunhofer ISE. NexWafe has developed monocrystalline wafers used in solar cell production, which consume substantially less energy than traditional wafers.
WOW Ventures, a Saudi VC firm, contributed to Tespack’s $2.35M Series A investment in September 2017. Tespack has developed a solar backpack that allows people to utilize off-grid electricity outdoors.
The KAUST Innovation fund, a seed fund at the King Abdullah University of Science and Technology, has also invested in two solar startups. In February 2017, KAUST contributed to QD Solar‘s $7.64M Series A round. QD Solar has developed technology that increases the energy output of solar panels, utilizing quantum dot technology to capture infrared energy that’s currently wasted.
The fund has also invested in NOMADD Desert Solar Solutions, which has developed a fully-automated system that cleans the dust from the surface of solar panels without using water or causing any other type of damage.

This report was created with data from CB Insights’ emerging technology insights platform, which offers clarity into emerging tech and new business strategies through tools like:
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If you aren’t already a client, sign up for a free trial to learn more about our platform.
Source: https://www.cbinsights.com/research/saudi-arabia-electric-vehicle-energy-investment/
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These 5 Emerging Technologies Could Help Reshape Manufacturing In A Post-Covid World
The Covid-19 pandemic has highlighted some of the major challenges facing manufacturers. We dig into 5 novel technologies that could improve supply chain resilience, boost production speed and flexibility, and more.
source: https://www.cbinsights.com/research/technologies-topics/
These 5 Emerging Technologies Could Help Reshape Manufacturing In A Post-Covid World
   July 29, 2020
The Covid-19 pandemic has highlighted some of the major challenges facing manufacturers. We dig into 5 novel technologies that could improve supply chain resilience, boost production speed and flexibility, and more.
The Covid-19 pandemic has shaken the global manufacturing industry.
This sweeping disruption has brought attention to some of the major ongoing challenges facing the sector and has highlighted the need to boost supply chain resilience, speed up production, and make products with higher degrees of precision.
Adding to this, the associated economic uncertainty has heaped pressure on manufacturers to increase efficiency and bring down costs.
But a number of emerging technologies could help address some of these challenges — transforming the space and complementing its steady march toward automation.
For example, embedded metrology is helping reduce manufacturing waste. High-speed sintering promises to make factories more adaptable. And light-based manufacturing could make it cheaper to produce highly intricate designs.
Using CB Insights data, we explore 5 emerging technologies that could reshape the manufacturing space and create new opportunities.
Table of contents
   Generative design
       What is generative design?
       How generative design is reshaping production
       Challenges and opportunities in generative design
   Embedded metrology
       What is embedded metrology?
       How embedded metrology is changing precision measurements
       Challenges and opportunities in embedded metrology
   High-speed sintering (HSS)
       What is high-speed sintering?
       How high-speed sintering is changing rapid prototyping and production
       Challenges and opportunities in high-speed sintering
   Light-based manufacturing
       What is light-based manufacturing?
       How light-based manufacturing is changing component assembly
       Challenges and opportunities in light-based manufacturing
   Nanotechnology
       What is nanotechnology?
       How nanotechnology is changing what can be made
       Challenges and opportunities in nanotechnology
1. Generative design
Whether fabricating new consumer products or producing new drugs, efficiency is one of the most common bottlenecks in manufacturing — but in many cases, this can be improved by the design of the manufactured product itself.
Even in ideal conditions, it takes time, effort, and significant investment to bring a new product to market. During a large-scale crisis like the Covid-19 pandemic, this problem can be exacerbated as manufacturers seek to respond to rapidly changing needs.
Generative design, an emerging field that uses machine learning to create products based on a broad set of criteria, could help speed up the manufacturing process and make it more adaptable in the future.
What is generative design?
Generative design is a process in which artificial intelligence (AI) and machine learning algorithms quickly produce multiple iterations of a design based on predefined specifications, including structural composition, materials, and available manufacturing methods.
Once a generative design system has been provided with these initial parameters, neural networks generate a broad range of designs to help identify the most efficient combinations of materials and specifications. Designers can tweak these permutations as they go, providing the neural network with data from which to “learn” about the designer’s preferences.
How generative design is reshaping production
Some industries have already applied generative design to create products that are more efficient to build and more effective in their use.
Aircraft manufacturer Airbus, for instance, relied on generative design to create a new partition for its A320 passenger aircraft, resulting in a design that was 45% lighter than previous iterations. Airbus estimates this could reduce its fleet’s annual carbon emissions by almost 500,000 metric tons.
Covid-19 has created an additional impetus for speed that could accelerate the adoption of generative design approaches.
For example, shortages of space in healthcare facilities have translated to a need for the rapid construction of emergency field hospitals, and generative design could make such operations faster, more efficient, and more cost-effective.
Chicago-based design and construction consultancy VIATechnik is working with the Quebec Wood Export Bureau (QWEB) to develop generative-designed, prefabricated structures for use in disaster relief efforts around the world.
VIATechnik’s virtual design and construction technology allowed the firm to create generative iterations of QWEB’s prefabricated buildings based on a range of criteria, including climate, terrain, and population density.
The generative nature of the designs means that planners can quickly and easily modify the specifications of the prefabricated structures based on changing needs, while still meeting criteria that allows them to be manufactured quickly.
One subset of the medical field that could also benefit from generative design is drug discovery.
Developing and manufacturing a new drug is often a lengthy process — averaging about a decade — and can cost billions of dollars.
IBM is looking to sidestep some of these delays and costs in its efforts to tackle Covid-19 by using generative modeling techniques. The company is designing antiviral molecules that specifically target the proteins of the underlying SARS-CoV-2 virus.
Researchers at IBM have trained neural networks to create simulations of molecular interactions and design structures that more effectively bind to SARS-CoV-2 proteins. This approach has the potential to speed up the discovery and production of new antiviral drugs that could help combat Covid-19 and other novel viruses in the future.
Challenges and opportunities in generative design
The generative design market is expected to grow to $321M in the coming years, according to CB Insights’ Industry Analyst Consensus market sizing tool. However, while generative design has the potential to speed up the time it takes to make a new product, the technology isn’t without its drawbacks.
For now, generative design systems are still reliant upon the input and guidance of human operators. This increases the cost of implementing a generative design system, since skilled operators are required to train the underlying AI.
Advancements in AI technologies may eventually allow generative design systems to operate more autonomously in the future, but the technology has yet to reach this level of sophistication.
The output of generative design systems is also largely dependent on the performance of the associated machine learning algorithms. Poorer-quality algorithms will result in poorer-quality designs.
Generative design systems may be able to rapidly iterate on hundreds of permutations of a design or molecular sequence in short periods of time, but this will be of little use to manufacturers if the resulting permutations are inferior to those created by conventional approaches.
2. Embedded metrology
The pandemic has underscored the need for adaptable manufacturing in times of crisis — as seen with companies like Ford and General Motors retooling their factories to make ventilators. But the uncertain economic conditions stemming from Covid-19 have also increased pressure on manufacturers to keep costs down and boost efficiency.
With defects being one of the leading causes of industrial waste, embedded metrology is a manufacturing technology that could reduce the cost of production while also boosting precision and adaptability.
What is embedded metrology?
Embedded metrology is an approach in which precision measurements are made at the same time as individual components are manufactured.
Typically, quality assurance (QA) checks of individually machined components are done on a batch basis at the end of the manufacturing process. Manufactured parts are randomly selected for QA testing and measured to ensure accuracy. In the event that the selected parts do not meet minimum quality standards, the affected batch is remanufactured.
Embedded metrology — also known as metrology-assisted assembly — relies on sophisticated sensors installed on specialized machinery and robotic manufacturing systems, which allow individual components to be precisely monitored and quality-tested as they are made.
This ensures that every component, rather than a random sample of components, is measured, avoiding the need to remanufacture entire batches if not necessary and reducing the likelihood of deficient products being shipped.
This approach could be especially useful for building components for use in aerospace, automotive, and medical applications, because even microscopic inaccuracies in individual parts can pose significant safety risks to passengers and patients and expose manufacturers to legal liability.
How embedded metrology is changing precision measurements
While Covid-19 has revealed critical vulnerabilities in global manufacturing supply chains, it has also highlighted the urgent need for flexible production environments that can be rapidly reconfigured to meet emerging needs. By reducing waste, decreasing lead time, and increasing overall accuracy, embedded metrological systems will be essential in creating a more adaptable global supply chain.
Global precision metrology group Renishaw provided an example of this in action when it began producing ventilators to meet the sudden demand for breathing apparatuses across Britain’s National Health Service (NHS).
Working to specifications developed by the Ventilator Challenge UK consortium, Renishaw’s production facilities in Gloucestershire and southern Wales have been producing machined components for use in ventilators using embedded metrology systems.
   “Ventilators are intricate and highly complex pieces of medical equipment and it is vital that we balance the twin imperatives of speed of delivery with the absolute adherence to regulatory standards that is needed to ensure patient safety.” — Dick Elsy, CEO of HVM Catapult and leader of Ventilator Challenge UK consortium
Prior to the emergence of Covid-19, Renishaw had never manufactured machined components for use in ventilators. But the company used embedded metrology to help manufacture the intricate parts needed to assemble ventilators without compromising on speed or accuracy and with minimal waste.
This kind of flexibility is likely to become increasingly important in the coming years, particularly if more governments around the world seek to mitigate supply chain vulnerabilities by encouraging onshoring of some manufacturing operations.
Challenges and opportunities in embedded metrology
Embedded metrological systems are transforming manufacturing by increasing accuracy, reducing waste, decreasing overall production time, and saving money. While metrology is likely to become more tightly integrated into manufacturing as a whole in the coming years, certain types of metrology systems may become more commonplace than others, most notably non-contact metrology.
Non-contact metrology systems typically rely on laser scanning, optical interferometry, and X-ray-computed tomography to conduct inspections without having to be maneuvered to measure a machined part. These technologies will likely see greater adoption in the near future as non-contact metrology is well-suited to help automate facilities.
However, despite the many benefits of embedded metrological tools in the assembly process and the sophistication of emerging metrological technologies, there remain barriers to the widespread adoption of the tech.
Several industries, including the medical devices sector, are likely to require additional final validation of individual components in order to comply with stringent regulatory requirements. This is especially relevant to the production of advanced critical-care machinery that contains highly sensitive components, which non-contact metrology systems may not yet be able to validate.
Another consideration facing manufacturers exploring embedded metrological systems is the cost of deployment. While assembly lines featuring embedded metrological systems can be set up as new factories are built, retrofitting existing hardware with embedded metrological measuring devices could be impractical or cost-prohibitive for many factories.
The impact of Covid-19 on global supply chains was swift and profound, but the blow to China’s manufacturing sector was particularly pronounced at the beginning of the pandemic. Amid the country’s outbreak, manufacturers reported operating at half their ordinary capacity, with many suffering substantial, prolonged reductions in their workforces.
While many factories in China have since resumed close-to-normal operations, the resiliency of global supply chains has become a significant concern for manufacturers around the world.
With many companies seeking to shore up vulnerabilities highlighted by the pandemic, 3D printing has once again emerged as a potential solution to some of the challenges of intricate, and at times fragile, international supply chains.
3. High-Speed Sintering
Although 3D printing, also referred to as additive manufacturing, has become increasingly commonplace over the past 10 years, the tech has not yet reached the potential that early hype promised. This could be changing, however, thanks to advancements in high-speed sintering.
What is high-speed sintering?
High-speed sintering (HSS) — sometimes known as ultrafast 3D printing — combines the benefits of 2 existing additive printing techniques: selective laser sintering and binder jetting. These allow HSS printers to print across significantly larger surface areas and use a broader range of materials.
Depending on the parameters of the individual printer, HSS can be 10-100x faster than ordinary 3D printing. According to its inventor Neil Hopkinson, an HSS printer with a print bed measuring 1 square meter could feasibly produce a flat-pack chair in just a few minutes.
In HSS, the strength and density of the printed product can be actively controlled by adjusting the amount of infrared light absorbed by the heat-sensitive ink used in the process. This dimension sets it apart from conventional 3D printing.
During initial tests of HSS, this capability allowed researchers to adjust the density of a printed product by up to 40%, a capability that could bring down manufacturing costs for some products.
At present, HSS printing techniques are best suited for various types of thermoplastics, which are commonly used to manufacture a wide range of products from airplane window panes to motorcycle helmet visors. HSS is also suitable for working with elastomers, which are frequently used to produce medical prostheses and fabrics such as nylon.
How high-speed sintering is changing rapid prototyping and production
Some companies have already begun exploring the possibilities of HSS. Among them is German chemical manufacturer Evonik, which develops thermoplastic powders and elastomers for use in HSS within the commercial 3D printing industry.
However, while HSS shows great promise, it is not yet widely used as a production method. This is primarily because additive manufacturing has mostly focused on rapid prototyping as opposed to rapid production.
   “Our everyday products have been improved considerably — for example, the all-electric car — yet the systems used to build these cutting-edge products are stuck in a previous decade. Innovation in spaces like high-speed metal additive manufacturing would pave the way for even better end products of the future.” — Lior Susan, founder of Eclipse Ventures
Developments in sintering technologies, particularly emerging technologies allowing for the 3D printing of objects using metals, will dramatically reshape how products are manufactured.
For example, China-based polymer printing company Farsoon Technologies has developed a method for the additive printing of objects using copper. This technique has allowed Farsoon’s scientists to print copper heat exchangers — a feat that signals a major shift in potential use cases for conventional additive manufacturing and HSS technologies.
Challenges and opportunities in high-speed sintering
The prolonged disruption to China’s manufacturing centers caused by Covid-19 was felt keenly around the world as the pandemic took hold. This prompted a number of governments and companies to reassess their manufacturing capabilities in a bid to make supply chains more resilient, a process which may drive investment in emerging manufacturing technologies like HSS in the coming years.
But ultrafast 3D printing could accomplish far more than shoring up vulnerabilities in distributed global supply chains. The tech will allow manufacturers to respond much more quickly to emerging crises, from pandemics to natural disasters, by offering a more flexible, adaptable manufacturing base.
However, there are limitations to the applications of HSS, one of the most notable being the materials used in ultrafast 3D printers. Although Farsoon Technologies’ additive copper printing technique carries potential across a large range of manufacturing applications, the metal powders necessary for this and similar processes pose significant safety risks due to their highly combustible nature.
Even though HSS printers can produce components very quickly, the safety precautions necessary to work safely with metal powders, as well as the often-lengthy post-production processes required when working with printed metal objects, could diminish some of the initial productivity gains.
Another potential challenge facing HSS is accuracy. For example, while current 3D printing technologies have been used to produce medical and personal protective equipment (PPE) such as masks and nasal swabs, the products often don’t meet the fluid barrier and air filtration standards necessary to safely treat Covid-19 patients in clinical environments.
HSS and 3D printing technologies are unlikely to single-handedly solve broader supply chain problems, but the tech is set to play a growing role as it matures.
4. Light-based manufacturing
The disruption caused by Covid-19 has added pressure to manufacturers to reduce costs and increase precision. Though still nascent, light-based manufacturing may one day help address these challenges across a broad range of industries.
What is light-based manufacturing?
Light-based manufacturing is an emerging technology in which light is used to manipulate tiny fragments of material suspended in a liquid. These fragments are then heated to fuse them together, creating a finished product.
The process is entirely contact-free, which could make it well-suited for the manufacturing of highly sensitive electrical components, such as microprocessors. The technique was pioneered by researchers in Dr. Steven Neale’s Micromanipulation Research Group at the University of Glasgow.
Light-based manufacturing relies on an advanced optical trapping technique known as “optoelectronic tweezers” to hold and manipulate small objects suspended in the liquid.
   “The forces formed by these optoelectronic tweezers have been compared to Star-Trek like tractor beams that can move objects through a medium with nothing touching them. This conjures up images of assembly lines with no robotic arms. Instead, discrete components assemble themselves almost magically as they are guided by the patterns of light.” — Dr. Steven Neale, University of Glasgow
The tweezers themselves are formed by a layer of silicon that creates an electrical field in the areas exposed to light, which reacts with particles or beads suspended in the liquid above the silicon. This technique allows for the manipulation of particles measuring as small as a nanometer — less than half the diameter of a strand of human DNA.
How light-based manufacturing is changing component assembly
Although light-based manufacturing shows promise for applications in the semiconductor and microprocessor industries, it is still an experimental technology in the early stages of R&D and is not yet being used commercially. However, researchers around the world are already beginning to unlock the potential of light-based manufacturing.
Hayden Taylor, an assistant professor of mechanical engineering at the University of California, Berkeley, is working on a technique known as computed axial lithography, which functions similarly to Neale’s method. In Taylor’s technique, the print volume is rotated relative to the light source, allowing for all points of a 3D object to be created simultaneously rather than sequentially.
Neale and his team are also researching the potential use of light-based manufacturing in the production of high energy density capacitors as an alternative to conventional batteries in mobile devices.
Others are exploring using optoelectronic tweezers in biotechnological applications, such as the manipulation of individual cells. Dr. Shuailong Zhang, a former member of Neale’s group in Glasgow, and researchers at the University of Toronto have developed an optoelectronic microbot for planned use in biotechnological research and drug delivery.
The microbot can be programmed to perform a range of actions at sub-millimeter dimensions, including the isolation of individual cells, the control of cell-to-cell interactions, and RNA sequencing.
Challenges and opportunities in light-based manufacturing
Aside from potential applications in the production of intricate electronic components, light-based manufacturing has the touted advantage of helping to reduce costs in mass-production environments. The use of optical tweezers could allow for faster, easier manipulation of tiny parts and, in some cases, could eliminate the need for costly robotic machinery to precisely move and solder individual components.
   “Optoelectronic tweezers are cost-effective and allow parallel micromanipulation of particles. In principle, we can move 10,000 beads at the same time. Combining this with our freeze-drying approach creates a very inexpensive platform that is suitable for use in mass production.” — Dr. Shuailong Zhang, University of Toronto
However, while the technique itself may prove cost-effective in the mass production of microscopic electrical components, existing factories cannot be easily modified or reconfigured to shift from traditional mechanized assembly lines to light-based manufacturing techniques. This may slow adoption of the tech even as it becomes more capable.
5. Nanotechnology
Nanotechnology — the science of working with matter at the molecular scale — has long been a mainstay of science fiction. But in recent years, nanotechnology has led to the production of new types of products in industries ranging from textiles to surgical medicine.
Amid the Covid-19 pandemic, some researchers are even turning to nanotechnology to help manufacture products to combat infectious diseases.
What is nanotechnology?
Nanotechnology is an umbrella term that encompasses a range of scientific disciplines focused on the manipulation of matter at the atomic, subatomic, and molecular levels. It is sometimes conflated with nanorobotics, a specialized subset of nanotechnology focusing on the development of microscopic robots.
There are 2 primary approaches to using nanotechnology in manufacturing (nanomanufacturing): top-down and bottom-up.
As the names imply, one technique is reductive, and the other is additive. In top-down nanomanufacturing, a larger block of material is systematically reduced until only the finished microscopic product remains. In bottom-up nanomanufacturing, components and products are built by gradually adding atomic- and molecular-level particles until the product is finished, in an iterative fashion analogous to traditional 3D printing.
How nanotechnology is changing what can be made
There are already dozens of everyday applications of nanotechnology across a range of sectors. Chemical manufacturers rely on nanocatalysts to create chemical reactions necessary to produce certain products, such as creating biodiesel from waste cooking oil. The automotive and aerospace manufacturing sectors make extensive use of nanocomposite coatings to reduce surface corrosion. Researchers are also using carbon nanotubes to improve water filtration systems.
In response to the Covid-19 pandemic, some nanotechnologists are examining ways in which nanoparticles can be used to create more effective protective equipment for medical personnel and frontline workers.
For example, researchers at KAIST in South Korea have developed a nanofiber technology that could improve the efficacy of medical face masks. Common face masks, such as the N95 masks typically used by medical professionals, are single-use only — the masks lose some of their protective properties when exposed to water, making them difficult to clean.
The team of scientists at KAIST, led by professor Il-Doo Kim, claim that their nanofiber mask fabric can effectively filter fine particulate matter even after being hand-washed more than 20 times.
Professor Il-Doo Kim of KAIST demonstrates his team’s nanofiber fabric for medical face masks. Source: KAIST
Nanomanufacturing is also being used for other preventative measures to control the spread of Covid-19. Researchers at Hong Kong University of Science and Technology (HKUST) developed an antiviral coating using nanotechnology that releases disinfectant over time from millions of microscopic nanocapsules. Researchers claim the coating, which can be applied to surfaces via an aerosol spray, can offer antimicrobial protection for up to 90 days after application.
Challenges and opportunities in nanotechnology
The Covid-19 pandemic has demonstrated a global need for inexpensive, easily manufactured, high-quality medical equipment to fight sudden outbreaks of disease. Many countries, including the US, have struggled with chronic shortages of PPE, and the efficacy of some of the PPE that medical professionals do have has been called into question by frontline medical staff and policymakers alike.
Nanotechnology may seem an unlikely solution to combat pathogens, but such approaches could become increasingly necessary as bacteria develop greater microbial resistance to antibiotics and even alcohol-based disinfectants.
Challenges relating to scaling nanomanufacturing for mass production could hinder its broader adoption across the manufacturing landscape — though its role in niche applications and in enabling the production of new types of intricate products is set to keep growing.
source: https://www.cbinsights.com/research/emerging-tech-reshape-manufacturing-post-covid-19/
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How GE, the World’s Most Active Industrial Internet of Things Investor, Uses CB Insights To Stay on Top  of IIoT Startups & Trends
To meet the challenge of managing knowledge around IIoT and accelerate internal collaboration, GE uses CB Insights. GE saw the potential of IIoT before virtually anyone else. And it was critical they did. For GE, a market leader in a diverse array of business lines ranging from jet engines to medical imaging to transportation, the productivity and revenue opportunities that IIoT unlocks are massive. GE saw the opportunity for IIoT technologies early. Through M&A, partnerships and investments, they excel at using startups and emerging tech companies as a way to bring this innovation to their organization. Notably, they’ve:
   Acquired LM Wind Power for $1.65B in October 2016 to bring their app capabilities to turbines.
   Invested in companies like Maana and Mocana, which  develop unique technologies related to manufacturing, big data and cybersecurity.
   Acquired ServiceMax and Meridium to accelerate its industrial app portfolio; acquired Wise.io and BitStew to strengthen its Predix platform.
The organization’s commitment to IIoT manifests itself in two groups with distinct but complementary goals to bring innovation to GE:
   GE Ventures — Offers entrepreneurs and startups access to  GE’s expertise, resources and capital to accelerate startup growth.
   GE Digital — Connects software, apps and analytics to  industrial businesses, enabling them to operate faster, smarter  and more efficiently.
Both GE Ventures and GE Digital are charged with keeping tabs on IIoT and also in sharing that knowledge within their teams and across the organization. Even in a visionary organization, knowledge management was a challenge. In a space growing as rapidly as IIoT and in an organization as expansive as GE, the discovery of companies and trends and associated discussion and collaboration among teams became incredibly important.
Historically, in order to track and discuss startup companies, GE Ventures and GE Digital team members relied on a mix of email, spreadsheets and offline conversations. But managing knowledge within two fast growing teams and across the enterprise in this manner presented ongoing challenges:
• Spreadsheet lists of companies were static unless manually updated and in a space growing as fast as IIoT, static doesn’t work.
• Discussion of specific companies or trends was happening in email and offline which means that there  was no aggregated view of these discussions.
   Spreadsheets and email make it difficult to onboard people from around the organization which both GE Ventures and GE Digital are trying to enable.
GE was unwilling to accept the limitations presented by traditional communications methods and looked for a better solution to meet their needs. Their biggest ideas deserved better. GE required a solution that would help bolster and maintain its knowledge of the rapidly evolving IIoT space, while also providing a centralized way for team members to collaborate and manage knowledge. Here, GE turned to CB Insights and our Collections capability, often dubbed a CRM for Innovation, to solve these challenges. First, the GE team cloned the Industrial Internet of Things Expert Collection that the CB Insights research team had
GE used CB Insights to transform how its teams collaborate. Just two months after adoption, GE Ventures and GE Digital have successfully added 15283 companies to its Collections, continuing to ensure its expertise in the IIoT landscape while easily communicating insights and sharing ideas across the enterprise. As a power user of Collections, GE team members are in close contact with the CB Insights Product leaders driving the Collections experience. “Our team is aggressively out in the market looking for and talking to industrial internet companies. And as a result, we see lots of very interesting companies daily. But with that volume, it was becoming increasingly important for us to keep that knowledge somewhere so we could share it both internally, with our GE Ventures colleagues and ultimately across the enterprise,” said Sanjay Kacholiya, MD, Corporate Development at GE Digital. “As a result, our team was quick to adopt Collections and take advantage of the improved collaboration that it enables. It has also already proven very useful in keeping us better informed and organized about the IIoT industry.”
source: https://www.cbinsights.com/case-studies/GE.pdf
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Oct 15, 2015
CB Insights: Predicting Startup Unicorns And Mastering Big Data Analytics For Private Companies
Gil Press Senior Contributor
Enterprise & Cloud
[ EXCERPTS ]
CB Insights is riding the Unicorn Boom, doubling its headcount since the beginning of the year, propelled by its unique database of companies and investors and everything there is to know about them. The frequency of “according to CB Insights” appearing in a wide range of media outlets has gone up dramatically this year. The fast-growing subscriber list for its engaging newsletter, bursting with visually-appealing data nuggets and topical analysis, is now at more than 100,000. Recently, it has supplied the New York Times with a list of the “50 Companies That May Be the Next Start-Up Unicorns.”
Doing M&As for American Express and managing, among other things, investments in companies trying to disrupt AmEx, Anand Sanwal, CB Insights’ co-founder and CEO found out how difficult it was to use traditional information providers such as Dow Jones and Thomson (“their products, in one word, are terrible,” he says). To find out what’s going on with startups and other private companies, people were spending a lot of time manually gathering data by calling investors and VCs. Besides, the scope of this data collection was severely limited by the fact that private companies do their best to keep their financial performance private.
The answer to this need was in the explosion of publicly available data on the Web. “Better understanding private companies by using public information was the germ of the idea for CB Insights,” says Sanwal.
So a new digital business was born. CB Insights uses big data tools to automate the data collection, crawling about 100,000 sources daily, and big data algorithms to analyze the data about investors, companies, and industries. Most important, it identifies and tracks the publicly available signals that serve as good indicators of the health of private companies, e.g., hiring statistics from job boards, news and sentiment about the news, and information about new partners and customers. “I don’t think any of these [signals] is going to be independently a smoking gun,” says Sanwal. “We build this mosaic of a private company that’s instructive in understanding its health.” Doing it since 2009, CB Insights has amassed a large historical record that allows it to pinpoint which signals are strong (serving as valid indicators of a company’s success or failure) and which are weak.
The Unicorn Boom has provided a lot of opportunities for CB Insights to demonstrate their predictive analytics skills and get lots of free publicity, although hunting unicorns is a very insignificant part of the business.
That vision was behind the development of a predictive analytics platform on top of high-quality database, serving as the foundation from which to launch a variety of applications or services targeted at specific audiences and needs.  In addition to a subscription-based access to its database, CB Insights has offered so far applications and tools for assessing the health of private companies and investors, mapping the links between investors and companies, tracking valuation and valuation multiples data, monitoring the health and growth potential of markets, and industry analytics.
CB Insights aims to be “the Bloomberg for private companies,” Sanwal tells his public audiences. But it’s more than that. “Our mantra internally is that probability trumps punditry,” he says. “We want to take on all of those people who make bold prognostications of where the world is going but they completely pull it out of [thin air]. We want to use data to inform the conversation about what’s next.”
© 2020 Forbes Media LLC. All Rights Reserved.
source: https://www.forbes.com/sites/monicamelton/2020/07/28/meet-the-founder-betting-on-voice-and-video-comments-to-make-the-internet-a-more-empathetic-place/#24549453584c
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March 04, 2014 11:00 PM
CB Insights grows the old-fashioned way
Judith Messina
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CB Insights, founded by Jonathan Sherry and Anand Sanwal, crawls 100,000 Web sources a day to uncover information about the health and wealth of private firms.
A product of NYU-Poly's Varick Street incubator, CB Insights is riding the big-data wave. Corporations are desperate to access and make use of the huge amounts of data on the Internet dealing with every aspect of people's lives.
CB Insights does that by crawling 100,000 Web sources every day to uncover information about the health and wealth of private firms: whom they hire and fire, how much Web traffic they get, how they are portrayed in the media and so on. It tracks venture deals and analyzes industry trends. Increasingly, it rates the health of closely held companies using Mosaic, a proprietary product that applies predictive algorithms to public data. Customers—from venture capitalists to law firms to the Fortune 500 in search of sales leads—buy industry analyses and private-company evaluations, data feeds and deal-flow information.
Microsoft's Beti Cung this year stopped her longtime subscription to Dow Jones Venture Source and now relies on reports from CB Insights. A director of corporate strategy for the software giant, Ms. Cung has been using CB Insights for about three years, originally as part of a team that was looking to partner with early-stage companies. Now she uses CB Insights reports to let higher-ups know about emerging trends and interesting companies that "might signal a shift in technology" or require them to reallocate resources.
source: https://www.crainsnewyork.com/article/20140305/TECHNOLOGY/140309956/cb-insights-grows-the-old-fashioned-way
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CIO Journal
Startup Funding Dwindles Due to Coronavirus Slowdown
Big companies that count on startup acquisitions as a form of R&D face smaller pipeline of promising technology ventures
March 25, 2020
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Early-stage funding for startups is drying up as the coronavirus outbreak puts investors on edge, spelling trouble for large corporations looking to snatch up innovative technology and talent.
Capital from seed-stage funding, often the first significant source of cash for new ventures, has declined by about 22% globally since January, according to an analysis this week by CB Insights, a market-intelligence company.
The company puts total private-market funding for startups at $67 billion in the first quarter, down from an initial forecast of $77 billion.
The declines are expected to be especially sharp for startups in hard-hit sectors, such as retail, travel and hospitality, said Anand Sanwal, CB Insights’ chief executive. Startups developing capabilities in areas such as telehealth, autonomous delivery, disease diagnosis and virtual learning are likely to fare better, he said.
Startups are a major source of emerging technology and skilled workers for large companies, which have been on a shopping spree in recent years for promising ventures—especially those developing advanced information-technology tools, such as data analytics, artificial intelligence and robotic process automation.
Without funding, many startups will fail before catching the eye of corporate buyers, leaving a critical gap in the technology development ecosystem, industry analysts say. Startups also help nurture tech talent, which has been in short supply in recent years.
Mark Schneider, chairman of New York Angels, an early-stage investment group, said roughly half of its members plan to decrease investments in startups that aren’t already in their portfolios, while 5% said they would cease investing altogether.
 “Fortune 500 companies need these new technologies more than ever,” Jonathan Lehr, general partner at enterprise-technology venture-capital fund Work-Bench, said, citing continued corporate demand in areas such as document automation and customer management software, among others.
Write to Angus Loten at angus.loten@wsj.com
source: https://www.wsj.com/articles/startup-funding-dwindles-due-to-coronavirus-slowdown-11585175702
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ENSURING THE WORLD’S SMARTEST ORGANIZATIONS ACCESS THE BEST STARTUPS
Background
In 2010, CB Insights approached the National Science Foundation with the idea that we could use publicly available information and a variety of non-traditional signals to assess the health of private companies.
Having worked at American Express before, our founders had seen the challenges of assessing the health of smaller private companies (a.k.a. “thin file” companies). We believed we could use the vast amounts of unstructured and semi-structured information that is being created to better understand the health of these opaque companies.
We proposed using machine learning and advanced language processing techniques to build a system that would solve for these challenges. The NSF provided several grants to CB Insights to develop this technology.
With NSF support, we worked towards a model dubbed Mosaic that would aggregate and synthesize information about these companies from disparate sources and programmatically assess the health of startups.
Think of Mosaic as a FICO score for startups. By using Mosaic, capital, partnerships, talent, time, and attention would flow to the right companies, thereby minimizing misallocations of these resources.
To illustrate the power of Mosaic, we worked with The New York Times to predict 50 future unicorns (companies that would eventually be valued at $1 billion or more) back in 2015. As of early 2019, 24 of them have hit that mark (48%).
If we were a venture firm, this kind of hit rate would make us legendary. Our secret weapon has been Mosaic.
What is mosaic?
Mosaic is a quantitative framework to measure the overall health and growth potential of private companies using non-traditional signals.
The Mosaic score is comprised of 3 individual models — what we call the 3 M’s, each relying on different signals (although all the signals utilized are not revealed for obvious reasons).
Market
The quality of the market or industry a company competes in is critical. If you are part of a hot industry, that serves as a tailwind to push you along. Conversely, being in an out of favor space means fewer investors, partners, media, and more.
The market model looks at the number of companies in an industry, the financing and exit momentum in the space, and the overall quality and quantity of investors participating in that industry.
Money
The money model assesses the financial health of a company, i.e. is it going to run out of money? Our model looks at burn rate, the quality of the investors and syndicate that may be part of the company, its financing position relative to industry peers & competitors, and more.
Momentum
The final model is momentum, where we look at a variety of volume and frequency signals including social media, news/media, sentiment, and partnership & customer momentum.
We look at these on an absolute and relative basis vs. peers/industry comparables. The relative piece is critical as it ensures that, for example, enterprise software companies who may get less media attention or who spend less time on social media are not penalized versus consumer-focused tech companies.
How do our customers use mosaic?
Corporate Innovation
Pinpoint fast-growing private companies to understand viable business models, products, and technologies
Corporate Strategy
See fast-growing markets and industries before anyone else to inform executives on strategic decisions
Competitive Intel / Market Research
Assess the health of startups competing in your industry to advise your build, buy, or partner strategy
Corporate Development and M&A
Monitor the health and growth potential of possible acquisition targets as part of your due diligence process
Corporate Venture Capital
Identify the startups with the highest growth potential to satisfy your corporate investment philosophy
Backed by the National Science Foundation
It is worth noting that this is a very hard problem to solve and one we’ve been tackling for years. And it is also a very important one. Private companies, especially those in high growth sectors, are the lifeblood of our economy and massive drivers of employment, innovation and commerce. Increasing their access to opportunities is a good thing for society.
Going forward, we look to integrate even more data signals into our Mosaic models for additional nuance and precision. To battle the inherent opacity challenge, we have developed and will continue to develop tools that ensure companies are putting the most accurate view of their performance in front of investors, customers, partners, and more. Currently, tens of thousands of companies and investors already update their data via The Editor.
We’re excited to extend the work we’ve done with Mosaic so far to demystify the health of emerging tech companies even further.
source:
https://www.cbinsights.com/company-mosaic
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