Thanks to a Google® Scholar email alert (key word: Aramco), I found the
following Open Access article.
The first thing that jumped out at me was the subject of the article … bioinformatics.
Authors of the article are affiliated with KAUST, King Abduliziz University,
and Saudi Aramco.
KAUST and King Abduliziz University I understand. The two universities are
engaged in a wide range of academic pursuits.
But why Saudi Aramco?
I don’t know, but for what it’s worth, I can speculate.
Saudi Aramco and the Saudi universities, including KAUST and King Abduliziz
University, have deep and synergistic relationships with each other.
Aramco employs massive computing resources to characterize its reservoirs in
order to enhance its ability to extract oil from those resources.
The big data acquired as a result of these characterizations must be analyzed.
This analysis requires DeepLearning in order to make the data useful.
DeepLearning algorithms created in the bioinformatics field can be adapted for
use in the reservoir characterization effort.
Accordingly, it makes sense for Aramco to make available to bioinformatics
researchers their vast computing resources. The researchers will benefit from
the use of Aramco’s resources, and Aramco will benefit from the results of
their research.
So what do you think … does the Aramco/KAUST relationship + synergy theory seem
plausible?
TIP #1:
Relationship + synergy applies to everything, like ExxonMobil, Chevron, Shell,
BP, and the various universities they are associated with.
TIP #2:
The logic for the relationship may not be linear. It may be as indirect as the
relationship described above.
Here are some details from the article.
The link at the end of this description will take you to the free full
text of the article.
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Bioinformatics, 2018, 0–0 doi:
10.1093/bioinformatics/xxxxx Advance Access Publication Date: 01 September 2018
Original Paper Sequence analysis
DeepGSR: An
optimized deep-learning structure for the recognition of genomic signals and
regions
Manal Kalkatawi 1, 2
Arturo Magana-Mora 1, 3
Boris Jankovic 1
Vladimir B. Bajic 1
1 King Abdullah University of Science and Technology, Computational Bioscience
Research Center, Thuwal 23955-6900, Saudi Arabia.
2 King Abdulaziz University, Faculty of Computing and Information Technology,
Jeddah 21589, Saudi Arabia.
3 Saudi Aramco, EXPEC-ARC, Drilling Technology Team, Dhahran, 31311, Saudi
Arabia.
Abstract
Motivation: Recognition of different genomic signals and regions (GSRs) in DNA is
crucial for understanding genome organization, gene regulation, and gene
function, which in turn generate better genome and gene annotations. Although
many methods have been developed to recognize GSRs, their pure computational
identification remains challenging. Moreover, various GSRs usually require a
specialized set of features for developing robust recognition models. Recently,
deep-learning (DL) methods have been shown to generate more accurate prediction
models than ‘shallow’ methods without the need to develop specialized features
for the problems in question. Here, we explore the potential use of DL for the
recognition of GSRs. Results: We developed DeepGSR, an optimized DL
architecture for the prediction of different types of GSRs. The performance of
the DeepGSR structure is evaluated on the recognition of polyadenylation
signals (PAS) and translation initiation sites (TIS) of different organisms:
human, mouse, bovine, and fruit fly. The results show that DeepGSR outperformed
the state-of-the-art methods, reducing the classification error rate of the PAS
and TIS prediction in the human genome by up to 29% and 86%, respectively.
Moreover, the cross-organisms and genome-wide analyses we performed, confirmed
the robustness of DeepGSR and provided new insights into the conservation of
examined GSRs across species. Availability and implementation: DeepGSR is
implemented in Python using Keras API; it is available as open-source software
and can be obtained at https://doi.org/10.5281/zenodo.1117159G.
Contact: vladimir.bajic@kaust.edu.sa
or manal.kalkatawi@kaust.edu.sa
Supplementary information: Supplementary data are available at Bioinformatics
online.
1 Introduction © The Author(s) 2018. Published by Oxford University Press. This
is an Open Access article distributed under the terms of the Creative Commons
Attribution Non-Commercial License
source: https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/bty752/5089227
Free Full text: https://watermark.silverchair.com/bty752.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAlcwggJTBgkqhkiG9w0BBwagggJEMIICQAIBADCCAjkGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMzsxvWuEXhCUDWHXKAgEQgIICCkJuVRgDn_yeWX5NyUSMOHBHpFSgahMs2YN8jxYEd87_rSm5_UlMoMFxCjPMXynMYpSs4P10Ef4-gOmXldMvy0Dgm9bigMVMGHpgwFqar436r8RoDxZpov5fHYpNeNUcyFSQIlOlW-z4DMFhfXZWYSkdnulBRAIK1-U7vaNhsuuJB4takgTZvPvTrj1PIODBRZHeljlvQcVJ4lyD2bfiXLDv681QwxbJ029_xXDjQTwYaOoHO_TNFBdDx5z8-ZV_0EGemIaImcZ3JhbdDWoD7146HGZVOkLqjML_q7zy4i7E32Gh-0GsbdOO9yfWktXb9SVqydwWt4CIQis0YUPvcSPER50DYWgTw2h2ysutmkFL_guDPL_VQ-Ud7kJXXxcWBDIijUaDTLO_TD6wVXbgTXdIRKRmebEFLmZkF5BUqXkw00Xy-qKmUNPCsmEIsn6RBfRN6Or5L4-jHAi0saVoHICJYcL3b0Jo5NvOWzH9nXCTPB9QFKx4QxcSdn2mUQT0CudzznCy4kGS0K1y8YCmPZm1enbgybdP3jDZev6v3w8hv8htsupOACYwqHb8arhqGKxrT3VzkRnO_ng_R-bxPRXLUGYAUUpt8kSyZF2Fuz7BpiGySwmHWaLl9ni4R3jEopJRLq6lqUZZhLkKvdTS5sSRHFNKdbvXmrFzY6Y_T2tq1yMSKv7xWuiCNg
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